Field-Realistic Tylosin Exposure Impacts Honey Bee Microbiota and Pathogen Susceptibility, Which Is Ameliorated by Native Gut Probiotics

ABSTRACT Antibiotics have been applied to honey bee (Apis mellifera) hives for decades to treat Paenibacillus larvae, which causes American foulbrood disease and kills honey bee larvae.One of the few antibiotics approved in apiculture is tylosin tartrate.This study examined how a realistic hive treatment regimen of tylosin affected the gut microbio

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Characterisation of the Trichinella spiralis deubiquitinating enzyme, TsUCH37, an evolutionarily conserved proteasome interaction partner.

Garlic Grater Trichinella spiralis is a zoonotic parasitic nematode that causes trichinellosis, a disease that has been identified on all continents except Antarctica.During chronic infection, T.spiralis larvae infect skeletal myofibres, severely disrupting their differentiation state.An activity-based probe, HA-Ub-VME, was used to identify deubiqu

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